Epidemiology of intestinal parasitic infections in Babol City, Iran, during a seven years period: Epidemiology of intestinal parasitic

Zahra Ahmadnia; Farzaneh Jafarian; Hossein Ghorbani; Alireza Firouzjahi; Arshiya Yahyazadeh-Jolodar; Rouzbeh Mohammadi-Abandansari; Sodeh Darvishi-Ganji; Roja Jafarian; Parham Mashaee

Authors

Zahra Ahmadnia Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0003-2289-7106
Farzaneh Jafarian Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0003-2302-5676
Hossein Ghorbani Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0002-8209-069X
Alireza Firouzjahi Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0002-4102-3781
Arshiya Yahyazadeh-Jolodar Department of Medicin, School of Medicine, Sari Branch, Islamic Azad University, Sari, Iran https://orcid.org/0009-0006-0979-0004
Rouzbeh Mohammadi-Abandansari Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0002-6697-2166
Sodeh Darvishi-Ganji Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0002-6968-3968
Roja Jafarian Department of Medicin, School of Medicine, Sari Branch, Islamic Azad University, Sari, Iran https://orcid.org/0000-0001-8517-5747
Parham Mashaee Student Research Committee, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0002-1877-3023

Keywords:

Infections, Intestinal Parasite, Entamoeba Histolytica, Epidemiology

Abstract

BACKGROUND: The north of Iran has a temperate and humid climate, leading to a higher prevalence of parasitic infections compared to other regions. This study aimed to determine the prevalence of intestinal parasitic infections in the northern part of Iran.

METHODS: This qualitative, retrospective, descriptive-analytical, and cross-sectional study was conducted from March 2017 to the end of March 2024. Data from 6962 patients recorded in the Hospital Information System (HIS) of Ayatollah Rouhani Teaching Hospital in Babol City, Mazandaran Province, Iran, were analyzed. Direct microscopic examination and formalin-ether concentration techniques were used to diagnose intestinal parasites. Data analysis was performed using SPSS software, with frequency (percentage) calculation and chi-square test (P < 0.05).

RESULTS: A total of 680 (9.76%) samples were infected with intestinal parasites. The prevalence was higher in women (54.30%) than in men (45.69%). Additionally, 55.80% of patients were from rural areas, while 44.19% were from urban areas. Entamoeba histolytica was the most common parasite, accounting for 32.05% of infections. The highest prevalence of parasitic infections was observed in the age group of 50-68 years (38%).

CONCLUSION: The study confirmed the presence of various intestinal parasites in stool samples. Women had a higher infection rate than men, and most infected individuals lived in rural areas. Entamoeba histolytica was the most prevalent parasite.

References

Alelign A, Mulualem N, Tekeste Z. Prevalence of intestinal parasitic infections and associated risk factors among patients attending Debarq Primary Hospital, northwest Ethiopia. PLoS One. 2024; 19(3): e0298767.

Heydarian P, Ashrafi K, Rahimi Esboei B, Mohe-Bali M, Kia EB, Aryaeipour M, et al. Emerging Cases of Fascioliasis in Lorestan Province, Western Iran: Case Series Report. Iran J Public Health. 2021; 50(1): 195-200.

Hajizadeh F, Galeh TM, Hosseini SA, Shariatzadeh SA, Hematizadeh A, Javidnia J, et al. Investigating intestinal parasitic infections with emphasis on molecular identification of Strongyloides stercoralis and Trichostrongylus colubriformis in north of Iran. Parasite Epidemiol Control. 2023; 22: e00312.

Asmar M, Ashrafi K, Amintahmasbi H, Rahmati B, Masiha A, Hadiani MR. Prevalence of Intestinal Parasitic Infections in the Urban Areas of Bandar Anzali, Northern Iran. J Guilan Univ Med Sci. 2014; 22(88): 18-25.

Hemmati N, Razmjou E, Hashemi-Hafshejani S, Motevalian A, Akhlaghi L, Meamar AR. Prevalence and Risk Factors of Human Intestinal Parasites in Roudehen, Tehran Province, Iran. Iran J Parasitol. 2017; 12(3): 364-73.

Hotez PJ. Empowering women and improving female reproductive health through control of neglected tropical diseases. PLoS Negl Trop Dis. 2009; 3(11): e559.

Štrkolcová G, Fiľakovská Bobáková D, Kaduková M, Schreiberová A, Klein D, Halán M, et al. Intestinal parasitic infections in children from marginalised Roma communities: prevalence and risk factors. BMC Infect Dis. 2024; 24(1): 596.

Halakou A, Khazan H, Behravan M, Mesgarian F, Bahrami F. Investigating the intestinal parasitic infections in Gonbad e Kavous in 2013. Exp Anim Biol. 2016; 4(4): 75-81.

Hajare ST, Gobena RK, Chauhan NM, Erniso F. Prevalence of Intestinal Parasite Infections and Their Associated Factors among Food Handlers Working in Selected Catering Establishments from Bule Hora, Ethiopia. Biomed Res Int. 2021; 2021: 6669742.

Ghorbani H, Ranaee M, Firouzjahi A, Ahmadnia Z, Rouhi S, Jafarian F, et al. Ten-year prevalence survey of Strongyloides stercoralis in patients referred to Rouhani hospital during 2011-2020 years: a brief report. Tehran Univ Med J. 2022; 80(5): 408–13.

Rezaee E, Jabrodini A, Pirouzi A, Heidari F. Prevalence of Intestinal Parasitic Infections in the Individuals Referred to Amir Almomenin Hospital of Gerash City, Iran, 2017-2018: A Short Report. J Rafsanjan Univ Med Sci. 2019; 18(5): 505-12.

Younes N, Behnke JM, Ismail A, Abu-Madi MA. Socio-demographic influences on the prevalence of intestinal parasitic infections among workers in Qatar. Parasit Vectors. 2021; 14(1): 63.

Brooker S, Clements AC, Bundy DA. Global epidemiology, ecology and control of soil-transmitted helminth infections. Adv Parasitol. 2006; 62: 221-61.

Barazesh A, Hazrati Tappeh KH, Mohammadzadeh H, Khashave SH. The study of the prevalence of intestinal parasitic infections in the personnel of private and governmental rehabilitation centers of Urmia. Nurs Midwifery Stud. 2007; 5(3): 101-6.

Chelkeba L, Mekonnen Z, Alemu Y, Emana D. Epidemiology of intestinal parasitic infections in preschool and school-aged Ethiopian children: a systematic review and meta-analysis. BMC Public Health. 2020; 20(1): 117.

Wattano S, Kerdpunya K, Keawphanuk P, Hunnangkul S, Loimak S, Tungtrongchitra A, et al. An Epidemiological Survey of Intestinal Parasitic Infection and the Socioeconomic Status of the Ethnic Minority People of Moken and Orang Laut. Trop Med Infect Dis. 2023; 8(3): 161.

Flaih MH, Khazaal RM, Kadhim MK, Hussein KR, Alhamadani FAB. The epidemiology of amoebiasis in Thi-Qar Province, Iraq (2015-2020): differentiation of Entamoeba histolytica and Entamoeba dispar using nested and real-time polymerase chain reaction. Epidemiol Health. 2021; 43: e2021034.

Debash MN, Kumie G, Sisay A, Gedfie S, Abebe W, Ashagre A, et al. Burden of intestinal parasites among diabetic patients in Africa: a systematic review and meta-analysis. BMC Infect Dis. 2025; 25(1): 54.

Banda A, Moyo DZ, Ncube N, Utete E, Machingura J, Gumbo T, et al. Gastrointestinal parasite prevalence, diversity and association in free-ranging Chacma baboon troops in a semi-arid savanna ecosystem of Zimbabwe. Int J Parasitol Parasites Wildl. 2024; 25: 101012.

Singer R, Xu TH, Herrera LNS, Villar MJ, Faust KM, Hotez PJ, et al. Prevalence of Intestinal Parasites in a Low-Income Texas Community. Am J Trop Med Hyg. 2020; 102(6): 1386-95.

Kantzanou M, Karalexi MA, Vrioni G, Tsakris A. Prevalence of Intestinal Parasitic Infections among Children in Europe over the Last Five Years. Trop Med Infect Dis. 2021; 6(3): 160.

Ahmed M. Intestinal Parasitic Infections in 2023. Gastroenterology Res. 2023; 16(3): 127-40.

Epidemiology of intestinal parasitic infections in Babol City, Iran, during a seven years period