Clinical symptoms related to patients with hyperinfection syndrome, infected with strongyloides stercoralis: Case series
Infection with Strongyloides stercoralis
Keywords:
Somatic Symptoms, Infections, Strongyloides StercoralisAbstract
BACKGROUND: Strongyloides stercoralis (S. stercoralis) is endemic in the northern provinces of Iran, and to identify it, in addition to clinical tests, clinical manifestations of the patient are also needed. This study aimed to investigate the clinical manifestations of patients with S. stercoralis infection.
CASE REPORT: Nine patients with S. stercoralis infection were investigated in this study. Out of 9 patients studied, 6 patients lived in the village. Clinical symptoms of patients included cough, cough with sputum, bloody sputum, fever, chills, respiratory disorder, diarrhea and melena, abdominal bloating, weakness, weight loss, blurred vision, double vision, headache, dizziness, severe burning behind the sternum, digestive disorders, heartburn, nausea, vomiting, lethargy, loss of appetite, purulent discharge from the ear, ear disorders, and imbalance. Fever, chills, and cough were common symptoms in almost all patients.
CONCLUSION: Clinical symptoms in patients were different and similar in cases where cough, fever, chills, and respiratory and digestive disorders were reported in almost all of them . Rapid identification and treatment of S. stercoralis is essential, especially in patients with immune system deficiency.
References
Yeh MY, Aggarwal S, Carrig M, Azeem A, Nguyen A, Devries S, et al. Strongyloides stercoralis Infection in Humans: A Narrative Review of the Most Neglected Parasitic Disease. Cureus. 2023; 15(10): e46908.
Puthiyakunnon S, Boddu S, Li Y, Zhou X, Wang C, Li J, et al. Strongyloidiasis--an insight into its global prevalence and management. PLoS Negl Trop Dis. 2014; 8(8): e3018.
Sari MA, Karimian P, Kia EB, Mohebali M, Aghakhani A, Darabi E, et al. Seroprevalence of Strongyloides stercoralis Infection in Patients with Hyperlipidemia: A Case-Control Study. Iran J Parasitol. 2024; 19(3): 341-8.
Dalimi A, Jaffarian F. Molecular Characterization of Strongyloides Stercoralis in Mazandaran Province, North of Iran. Arch Razi Inst. 2024; 79(3): 513-8.
Shafaghi A, Akhavan K, Hajizade H, Joukar F, Asgharnezhad M, Mansour ghanaei F. Disseminated Strongyloidiasis Following High-Dose Prednisolone Administration (A Case Report). J Guilan Univ Med Sci. 2012; 21(83): 95-100.
Khanmohammadi M, Javadi Mamagani A, Rezamand A, Mahami Oskouei M, Shahbazi A, Fallah E, et al. Case Report of a Strongyloides stercoralis infection in a child with acute lymphocytic leukemia in Tabriz, Iran. Med J Tabriz Univ Med Sci Health Serv. 2013; 35(5): 88-91.
Buonfrate D, Bisanzio D, Giorli G, Odermatt P, Fürst T, Greenaway C, et al. The Global Prevalence of Strongyloides stercoralis Infection. Pathogens. 2020; 9(6).
Vinh LD, Thach NK, Quang HH, Binh DN, Hanh TTD, Toàn NM, et al. A study implementing real-time PCR to identify Strongyloides species of third-stage larvae in human stool samples from Southern Vietnam. Infect Med (Beijing). 2023; 2(3): 229-36.
Moradali F, Afshin B, Rahim T. Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012. J Maz Univ Med Sci. 2017; 27(149): 187-91.
Nilforoushan MR, Kia EB, Mirhendi H, Rezaei S, Moubedi I, Maraghi S. Strongyloidiasis hyperinfection syndrome in Khouzestan province, Southwest Iran and molecular characterization of isolates recovered from the patients. Int J Inf Technol Decis Mak. 2007; 12(36): 45-8.
Xu Q, Xi X, Feng D, Sang Q, Sheng Y, Ding R, et al. A case report: Severe disseminated infection caused by Strongyloides stercoralis in an immunocompromised patient by metagenomic next-generation sequencing. Front Cell Infect Microbiol. 2023; 13: 1082412.
Ramezanzadeh K, Sharifzadeh G, Saljughi M, Moodi M, Ibrahimzadeh A. An Epidemiological Study of the Infectious Diseases of Older Adults Hospitalized in Hospitals Affiliated to Birjand University of Medical Sciences, in 2016. Salmand: Iran J Ageing. 2019; 14(3): 298-309.
Cabral SL, Deveza N, Baptista JP, Martins P. Disseminated Strongyloides stercoralis Infection Associated with Endogenous Hypercortisolism - A Case Report. Eur J Case Rep Intern Med. 2020; 7(7): 001509.
Ghorbani H, Ranaee M, Firouzjahi A, Ahmadnia Z, Rouhi S, Jafarian F, et al. Ten-year prevalence survey of Strongyloides stercoralis in patients referred to Rouhani hospital during 2011-2020 years: a brief report. Tehran Univ Med J. 2022; 80(5): 408-13.
Henriquez-Camacho C, Gotuzzo E, Echevarria J, White AC, Jr., Terashima A, Samalvides F, et al. Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. Cochrane Database Syst Rev. 2016; 2016(1): CD007745.
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