Frequency and characteristics of Brucellosis in Golestan Province, Iran
DOI:
https://doi.org/10.22122/cdj.v8i3.522Keywords:
Brucellosis, Brucella Infection, IranAbstract
BACKGROUND: Brucellosis is a common widespread zoonotic disease between humans and livestock with significant economic and health problems caused by various species of Brucella. The disease is a significant public health issue throughout the world and one of the most socioeconomic problems in many developing countries. This study aimed to report the information available at the Provincial Health Center about the frequency and characteristics of patients with Brucellosis in Golestan Province, Iran.
METHODS: This study was analytic-descriptive cross-sectional. The study population included all patients with Brucellosis diagnosed from 2011 to 2015 in the health center of Golestan Province, based on the serological method. The data gathering tool was a questionnaire that included demographic information, clinical presentation and examinations, history of exposure, laboratory findings, and treatment protocols. Descriptive statistics were reported as frequency and mean ± standard deviation (SD) and analyzed by SPSS software.
RESULTS: In this study, a total of 1788 cases of Brucellosis were reported. The number of male cases was 1163 (65.04%) and female cases were 625 (34.95%). People who had a history of contact with infected animals were younger than the others. Musculoskeletal pain (79.69%) and fever (76.45%) were the most commonly reported clinical symptoms.
CONCLUSION: Overall, the results indicate that Brucellosis is still a health problem in the province. The high incidence of Brucellosis in villages, the lack of full coverage of animal vaccination, and the link between the disease and livestock businesses are significant.
References
Khosravani A, Afshoun E, Yazdan Panah B. Seroepidemiological study of brucellosis in high risk groups in Boyerahmad 2005. Armaghane-danesh 2007; 11(4): 89-96. [In Persian].
Musallam II, Abo-Shehada MN, Hegazy YM, Holt HR, Guitian FJ. Systematic review of brucellosis in the Middle East: Disease frequency in ruminants and humans and risk factors for human infection. Epidemiol Infect 2016; 144(4): 671-85.
Adesokan HK, Alabi PI, Ogundipe MA. Prevalence and predictors of risk factors for Brucellosis transmission by meat handlers and traditional healers' risk practices in Ibadan, Nigeria. J Prev Med Hyg 2016; 57(3): E164-E171.
Germeraad EA, Hogerwerf L, Faye-Joof T, Goossens B, van der Hoek W, Jeng M, et al. Low seroprevalence of brucellosis in humans and small ruminants in the Gambia. PLoS One 2016; 11(11): e0166035.
Golsha R, Hezareh A, Golshah E, Golshahi G. Presentation of brucellosis in northeast of Iran: A 5-year study. Electronic Physician 2011; 3: 407-8.
Rahman MS, Faruk MO, Her M, Kim JY, Kang SI, Jung SC. Prevalence of brucellosis in ruminants in Bangladesh. Veterinarni Medicina 2011; 56(8): 379-85.
Agasthya AS, Isloor S, Krishnamsetty P. Seroprevalence study of human brucellosis by conventional tests and indigenous indirect enzyme-linked immunosorbent assay. The Scientific World Journal 2012; 2012: 104239.
Mirnejad R, Jazi FM, Mostafaei S, Sedighi M. Molecular investigation of virulence factors of Brucella melitensis and Brucella abortus strains isolated from clinical and non-clinical samples. Microb Pathog 2017; 109: 8-14.
Mostafavi E, Asmand M. Trend of Brucellosis in Iran from 1991 to 2008. Iran J Epidemiol 2012; 8(1): 94-101. [In Persian].
Nikokar I, Hosseinpour M, Asmar M, Pirmohbatei S, Hakeimei F, Razavei MT. Seroprevalence of Brucellosis among high risk individuals in Guilan, Iran. J Res Med Sci 2011; 16(10): 1366-71.
Poorhajibagher M, Pagheh A, Nasrollahi M, Mesgarian F, Badiee F, Ajami A. The evaluation of seroprevalence of brucellosis in patients refering to health care center of Gonbad Kavoos, 2009-11. J Mazandaran Univ Med Sci 2012; 22(90): 82-6. [In Persian].
Ramos TR, Pinheiro Junior JW, Moura Sobrinho PA, Santana VL, Guerra NR, de Melo LE, et al. Epidemiological aspects of an infection by Brucella abortus in risk occupational groups in the microregion of Araguaina, Tocantins. Braz J Infect Dis 2008; 12(2): 133-8.
Njeru J, Melzer F, Wareth G, El-Adawy H, Henning K, Pletz MW, et al. Human brucellosis in febrile patients seeking treatment at remote hospitals, northeastern Kenya, 2014-2015. Emerg Infect Dis
; 22(12): 2160-4.
Tumwine G, Matovu E, Kabasa JD, Owiny DO, Majalija S. Human brucellosis: sero-prevalence and associated risk factors in agro-pastoral communities of Kiboga District, Central Uganda. BMC Public Health 2015; 15: 900.
Abbasi A, Jafarpour H, Khodavandegari Z, Rezaei A, Amirkhanlou S. Report of the clinical features of patients with leptospirosis in Golestan, Iran, 2011-2015: Based on information available at the provincial health center. Chron Dis J 2018; 6(4): 164-70.
Pourmohammadi B, Motazedian MH, Kalantari M. Rodent infection with Leishmania in a new focus of human cutaneous leishmaniasis, in northern Iran. Ann Trop Med Parasitol 2008; 102(2): 127-33.
Sharif M, Nasrolahei M, Ziapour SP, Gholami S, Ziaei H, Daryani A, et al. Toxocara cati infections in stray cats in northern Iran. J Helminthol 2007; 81(1): 63-6.
Ebrahimpour S, Bayani M, Moulana Z, Hasanjani Roushan MR. Skeletal complications of brucellosis: A study of 464 cases in Babol, Iran. Caspian J Intern Med 2017; 8(1): 44-8.
Zeinalian DM, Fadaei NR, Ramazanpour J. Epidemiological features of human brucellosis in central Iran, 2006-2011. Public Health 2012; 126(12): 1058-62.
Hasanjani Roushan MR, Ebrahimpour S, Moulana Z.
Different Clinical Presentations of Brucellosis. Jundishapur J Microbiol 2016; 9(4): e33765.
Hosseini Sm, Amani R, Razavimehr SM, Moshrefi A, Aghajanikhah M, Ohammad H, et al. Epidemiology of brucellosis in Amol city from 2011 TO 2013. Beyhagh 2016; 21(36): 1-7. [In Persian].
Mosavi H, Shavisi N, Mostafavi E. Epidemiological features survey of Malta fever in Gylangharb city, Kermanshah province. Journal of Zoonoses Research 2014; 1(2): 31-8. [In Persian].
Earhart K, Vafakolov S, Yarmohamedova N, Michael A, Tjaden J, Soliman A. Risk factors for brucellosis in Samarqand Oblast, Uzbekistan. Int J Infect Dis 2009; 13(6): 749-53.
Ebrahimpour S, Youssefi MR, Karimi N, Kaighobadi M, Tabaripour R. The prevalence of human Brucellosis in Mazandaran province, Iran. Afr J Microbiol Res 2012; 6(19): 4090-4.
Taheri Soodejani M, Lotfi Mh, Ghaderi A, Reisi A, Mohammadzadeh M. Epidemiology of brucellosis in Shahr-e-Kord from 2010 to 2014. J Jahrom Univ Med Sci 2016; 14(1): 1-7. [In Persian].
Ghasemian R, Jafarpour H, Davoodi L, Movasagh S, Razavi A. Epidemiological and clinical survey of patients with spondylitis. J Mazandaran Univ Med Sci 2019; 29(180): 5-67. [In Persian].