Report of the clinical features of patients with leptospirosis in Golestan, Iran, 2011-2015: Based on information available at the provincial health center

Abdullah Abbasi, Hamed Jafarpour, Zahra Khodavandegari, Arash Rezaei, Saeid Amirkhanlou

DOI: 10.22122/cdj.v6i4.328

Abstract


BACKGROUND: Leptospirosis is a zoonotic disease with a global distribution that is caused by pathogenic spirochetes of Leptospira. It has a global spread, but it is more common in warm and tropical regions. In developing countries such as Iran, it is considered as a work-related illness and occurs mostly in farmers, ranchers, slaughterhouse workers, butchers, and fishermen in the warm seasons of the year. The aim of this study was to report the information available at the provincial health center about the clinical features of patients with leptospirosis in Golestan province, Iran, from 2011 to 2015.

METHODS: This cross-sectional descriptive study surveyed all patients with leptospirosis in Golestan provincial health center from 2011 to 2015. All information was collected by a self-designed checklist that its reliability was approved by three infectious specialists. In case of defective files, patients were contacted. The collected data were analyzed by an epidemiologist via SPSS software.

RESULTS: In this study, during the years of 2011 to 2015, 75 cases of leptospirosis were recorded. 50 cases (66.6%) were men and 25 (33.3%) were women. The most common complaint of patients at referral was fever (70 cases, 93.33%).. The most complained problem after fever (93.33%) was musculoskeletal pain and jaundice reported 57.33% and 54.66%, respectively.

CONCLUSION: It is important to pay attention to this disease in farmers and villagers, especially in agricultural seasons. Due to the high prevalence, morbidity, and mortality of leptospirosis, early diagnosis based on common symptoms is important. Healthcare centers in each area are required to recognize common diseases to reduce irreversible complications.


Keywords


Leptospirosis; Zoonotic Disease; Iran

Full Text:

PDF

References


Davoodi A, Najafi N, Tayebi A, Alian S, Delavarian L. Pulmonary involvement in leptospirotic patients. J Mazandaran Univ Med Sci 2011; 21(85): 69-74.

[In Persian].

Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. harrison's principles of internal medicine. 19ed ed. New York, NY: McGraw Hill Professional; 2015.

Rafiei A, Hedayati Zadeh Omran A, Babamahmoodi F, Alizqadeh Navaee R, Valadan R. Review of leptospirosis in Iran. J Mazandaran Univ Med Sci 2012; 22(94): 102-10. [In Persian].

Costa F, Hagan JE, Calcagno J, Kane M, Torgerson P, Martinez-Silveira MS, et al. Global morbidity and mortality of leptospirosis: A systematic review. PLoS Negl Trop Dis 2015; 9(9): e0003898.

Honarmand H, Eshraghi S. Detection of Leptospires serogroups, which are common causes of human acute leptospirosis in Guilan, Northern Iran. Iran J Public Health 2011; 40(1): 107-14. [In Persian].

Ghanaie F, Fallah M, Jafarshad R, Jokar A, Heydarzadeh H, Honarmand H. Clinical manifestations of leptospirosis in Guilan province. Iran J Infect Dis Trop Med 2008; 13(42): 53-6.

Shojaee J, Hosseini A, Abedi G, Bayatani A, Yazdani Cherati J, Kaveh F, et al. Spatial pattern and distribution of leptospirosis in Mazandaran province using geographic information system. J Mazandaran Univ Med Sci 2015; 25(131): 151-4. [In Persian].

Alavi SM, Khoshkho MM. Seroprevalence study of leptospirosis among rice farmers in Khuzestan province, South west Iran, 2012. Jundishapur J Microbiol 2014; 7(7): e11536.

Javid N, Dadgar T, Khodabakhshi B, Bazour M, Sedaghat M, Bakhshandeh-nosrat S, et al. Seroepidemiology of anti-leptospira antibody in Golestan province, North of Iran. International Journal of Molecular and Clinical Microbiology 2012; 2(1): 124-7. [In Persian].

Esmaeili S, Hashemi Shahraki A, Bagheri Amiri F, Karimi M, Mostafavi E. Serological survey of leptospirosis among different groups in western Iran. Trop Doct 2017; 47(2): 124-8.

Babamahmodi F, Motamed N, Mahdavi M, Nickhah F, Qavi Bonyeh K. Seroepidemiological study of leptospirosis in Ghaemshahr Mazandaran province-Iran, Sept-Oct 2004. J Mazandaran Univ Med Sci 2006; 16(53): 51-6. [In Persian].

Sethi S, Sharma N, Kakkar N, Taneja J, Chatterjee SS, Banga SS, et al. Increasing trends of leptospirosis in northern India: A clinico-epidemiological study. PLoS Negl Trop Dis 2010; 4(1): e579.

Zakeri S, Sepahian N, Afsharpad M, Esfandiari B, Ziapour P, Djadid ND. Molecular epidemiology of leptospirosis in northern Iran by nested polymerase chain reaction/restriction fragment length polymorphism and sequencing methods. Am J Trop Med Hyg 2010; 82(5): 899-903.

Esmaeili R, Hesamzadeh A, Alizadeh-Navaei R, Haghshenas MH, Alhani F. Incidence of leptospirosis in Mazandaran Province, north of Iran: A one year survey. Pak J Biol Sci 2009; 12(19): 1330-3.

Golsha R, Khodabakhshi B, Rahnama A. Leptospirosis in Golestan province in Iran (Reports of twelve cases). J Gorgan Univ Med Sci 2007; 9(2): 76-80. [In Persian].

Najafi N, Davoudi AR, Alian S, Ahangarkani F, Asghari E. Clinical and laboratory findings on complication in patients with leptospirosis in Mazandaran Province, Iran. Arch Clin Infect Dis 2015; 10(3): e24695.


Refbacks

  • There are currently no refbacks.


Creative Commons Attribution-NonCommercial 4.0

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.