Relationship between asthma and related factors of birth
DOI:
https://doi.org/10.22122/cdj.v2i2.41Keywords:
Asthma, Children, Birth-Related FactorsAbstract
BACKGROUND: Asthma is the most common chronic disease of childhood that causes disturbance in the physical, emotional, mental health, and different information has been mentioned on its risk factors, including factors associated with birth. Therefore, in this study, the relationship between children asthma and factors associated with birth was studied.
METHODS: This case-control study was performed on 50 children with asthma as the case group and 150 children hospitalized without asthma as the control group (after matched for age and sex) in an age range of 4-14 years old. Information required on factors affecting asthma was recorded for both groups. Data analysis was performed using SPSS for Windows software.
RESULTS: The results of this study showed that the majority of children in the case group were males born through cesarean operation (C-section). A significant difference was seen between two groups in terms of factors such as preterm [odds ratio (OR) = 3.27, confidence interval (CI) 95% = 1.57-6.81] and family history of asthma
(OR = 8.50, CI 95% = 4.10-17.60). Regression model of relational variables with asthma show that the family history of asthma was most effective determinant on birth-related factors of asthma.
CONCLUSION: The findings of this study showed that positive family history of the disease and premature-birth in infant correlates significantly and directly with asthma occurrence in children. Thus, it is recommended to make further follow-ups in providing prenatal care and early diagnosis of the disease.
References
Gerland MF, Barnes M, Barnes PJ, Bateman ED, Becker A, Drazen JM, et al. Global strategy for Asthma management and prevention Gina reports [Online]. [cited 2010]; Available from: URL:
http://www.ginasthma.org/local/uploads/files/GINA_Report_2010.pdf
Kercsmar C. Exhaled nitric oxide in the diagnosis and management of childhood asthma. Ther Adv Respir Dis 2010; 4(2): 71-82.
Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004; 59(5): 469-78.
Byers DE, Holtzman MJ. Alternatively activated macrophages as cause or effect in airway disease. Am J Respir Cell Mol Biol 2010; 43(1): 1-4.
Murray CS, Custovic A, Lowe LA, Aldington S, Williams M, Beasley R, et al. Effect of addition of salmeterol versus doubling the dose of fluticasone propionate on specific airway resistance in children with asthma. Allergy Asthma Proc 2010; 31(5): 415-21.
Yancey SW, Knobil K, Kral K. No association of catastrophic events with Advair. Am J Med 2010; 123(10): e15.
Ownby DR. Pet dander and difficult-to-control asthma: The burden of illness. Allergy Asthma Proc 2010; 31(5): 381-4.
Heidarnia MA, Entezari A, Moein M, Mehrabi Y, Pourpak Z. Prevalence of asthma symptom in Iran: a meta-analysis. Pejouhesh 2007; 31(3): 217-25. [In Persian].
Marcdante K, Kliegman RM, Behrman RE, Jenson HB. Nelson Essentials of Pediatrics. Philadelphia, PA: Elsevier Health Sciences; 2010. p. 953-70.
Martel MJ, Rey E, Malo JL, Perreault S, Beauchesne MF, Forget A, et al. Determinants of the incidence of childhood asthma: a two-stage case-control study. Am J Epidemiol 2009; 169(2): 195-205.
Subbarao P, Mandhane PJ, Sears MR. Asthma: epidemiology, etiology and risk factors. CMAJ 2009; 181(9): E181-E190.
Sherriff A, Peters TJ, Henderson J, Strachan D. Risk factor associations with wheezing patterns in children followed longitudinally from birth to 3(1/2) years. Int J Epidemiol 2001; 30(6): 1473-84.
Spahr JE, Krawiec ME. The early origins of asthma: nature, nurture, or parturition? Ann Allergy Asthma Immunol 2005; 94(2): 211-2.
Hakansson S, Kallen K. Caesarean section increases the risk of hospital care in childhood for asthma and gastroenteritis. Clin Exp Allergy 2003; 33(6): 757-64.
Wilcox AJ. The Medical Birth Registry of Norway - An international perspective. Norsk Epidemiologi 2007; 17(2): 103-5.
Kerkhof M, Koopman LP, van Strien RT, Wijga A, Smit HA, Aalberse RC, et al. Risk factors for atopic dermatitis in infants at high risk of allergy: the PIAMA study. Clin Exp Allergy 2003; 33(10): 1336-41.
Rust GS, Thompson CJ, Minor P, Davis-Mitchell W, Holloway K, Murray V. Does breastfeeding protect children from asthma? Analysis of NHANES III survey data. J Natl Med Assoc 2001; 93(4): 139-48.
Fiocchi A, Terracciano L, Martelli A, Guerriero F, Bernardo L. The natural history of childhood-onset asthma. Allergy Asthma Proc 2006; 27(3): 178-85.
Adkinson NF, Busse WW, Bochner BS, Holgate ST. Middleton's allergy. Philadelphia, PA: Mosby/Elsevier; 2008. p. 715-35.
Hockenberry MJ, Wilson D, Wong DL. Wong's Nursing Care of Infants And Children. Philadelphia, PA: Mosby/Elsevier; 2007.
Himes BE, Lasky-Su J, Wu AC, Wilk JB, Hunninghake GM, Klanderman B, et al. Asthma-susceptibility variants identified using probands in case-control and family-based analyses. BMC Med Genet 2010; 11: 122.
Kiechl-Kohlendorfer U, Horak E, Mueller W, Strobl R, Haberland C, Fink FM, et al. Neonatal characteristics and risk of atopic asthma in schoolchildren: results from a large prospective birth-cohort study. Acta Paediatr 2007; 96(11): 1606-10.
Metsala J, Kilkkinen A, Kaila M, Tapanainen H, Klaukka T, Gissler M, et al. Perinatal factors and the risk of asthma in childhood-a population-based register study in Finland. Am J Epidemiol 2008; 168(2): 170-8.
Rajaeifard AR, Moosavi Zadeh A, Pourmahmoudi A, Naeimi E, Hadinia A, Karimi A. Evaluation of Prevalence and Related Factors of Pediatric Asthma in Children Under Six Years Old With Logistic Regression and Probit. Armaghane-danesh 2011; 16(3): 272-81. [In Persian].
Klinnert MD, Nelson HS, Price MR, Adinoff AD, Leung DY, Mrazek DA. Onset and persistence of childhood asthma: predictors from infancy. Pediatrics 2001; 108(4): E69.
Nabavi M, Ghorbani R, Nabavi M, Hoseinzadeh Y. Prevalence of food allergy in asthmatic children under 18 years of age in Semnan-Iran in 2007-2008. Koomesh 2010; 11(3): 162-8. [In Persian].
Bilan N, Shiva S. Evaluation of risk factors in children 2-8 years of age with asthma referred to the outpatient clinic of Tabriz University of Medical Sciences. Med J Tabriz Univ Med Sci 2007; 29(3): 47-50. [In Persian].
Ghaffari J, Nazari Z, Gharegozlou M. Evaluating the relationship of the pre-term, method of delivery and breastfeeding with asthma. J Mazandaran Univ Med Sci 2008; 18(65): 87-900. [In Persian].
Dik N, Tate RB, Manfreda J, Anthonisen NR. Risk of physician-diagnosed asthma in the first 6 years of life. Chest 2004; 126(4): 1147-53.
Mohammadzadeh I, Babazadeh EF, F, Alizadeh Navaei R. Association between Asthma in Children and Mode of Delivery. J Babol Univ Med Sci 2009; 11(2): 38-53. [In Persian].
Werner A, Ramlau-Hansen CH, Jeppesen SK, Thulstrup AM, Olsen J. Caesarean delivery and risk of developing asthma in the offspring. Acta Paediatr 2007; 96(4): 595-6.
Juhn YJ, Katusic SK, Weaver AL, Yunginger JW. Assessment of the association between cesarean section and subsequent development of childhood asthma: A population-based cohort study. J Allergy Clin Immunol 2005; 115(2S): S201.
Miri Farahani L, Abbasi Shavazi M. Caesarean Section Change Trends in Iran and Some Demographic Factors Associated with them in the Past Three Decades. J Fasa Univ Med Sci 2012; 2(3): 127-34. [In Persian].
Tollanes MC, Moster D, Daltveit AK, Irgens LM. Cesarean section and risk of severe childhood asthma: a population-based cohort study. J Pediatr 2008; 153(1): 112-6.
Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol 2006; 16(5): 341-6.
Maitra A, Sherriff A, Strachan D, Henderson J. Mode of delivery is not associated with asthma or atopy in childhood. Clin Exp Allergy 2004; 34(9): 1349-55.
van Beijsterveldt TC, Boomsma DI. Asthma and mode of birth delivery: a study in 5-year-old Dutch twins. Twin Res Hum Genet 2008; 11(2): 156-60.
Kramer MS, Matush L, Vanilovich I, Platt R, Bogdanovich N, Sevkovskaya Z, et al. Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial. BMJ 2007; 335(7624): 815.
Ssenyonga R, Muwonge R, Nankya I. Towards a better understanding of exclusive breastfeeding in the era of HIV/AIDS: a study of prevalence and factors associated with exclusive breastfeeding from birth, in Rakai,Uganda. J Trop Pediatr 2004; 50(6): 348-53.
Fatholapoor A, Moridi G. Survey prevalence of asthma in children under three years of the relationship between breastfeeding and certain individual characteristics of the children referred to health centers in 1385 sanandaj. Proceedings of the 6th Conference of the Immunology, Asthma & Allergy; 2007 May 22-24; Tehran, Iran. [In Persian].
Mehrabi S, Delavare AR, Moradi GH, Ghaderi E. Bronchial asthma prevalence in the 64-15 years of Kurdistan 2007. Iran J Epidemiol 2008; 4(3-4): 93-8. [In Persian].
Sole D, Cassol VE, Silva AR, Teche SP, Rizzato TM, Bandim LC, et al. Prevalence of symptoms of asthma, rhinitis, and atopic eczema among adolescents living in urban and rural areas in different regions of Brazil. Allergol Immunopathol (Madr) 2007; 35(6): 248-53.
Sharifi L, Pourpak Z, Bokaie S, Karimi A, Movahedi M, Gharaghozlou M, et al. Childhood asthma prevalence and parents' daily cigarette smoking: a case-control study. Tehran Univ Med J 2009; 67(9): 655-60.
Eagan TM, Bakke PS, Eide GE, Gulsvik A. Incidence of asthma and respiratory symptoms by sex, age and smoking in a community study. Eur Respir J 2002; 19(4): 599-605.Eur Respir J 2002; 19(4):599-605.Eur Respir J 2002; 19(4):599-605.