The relationship between the adequacy of hemodialysis and laboratory parameters
DOI:
https://doi.org/10.22122/cdj.v5i1.226Keywords:
Dialysis, Hemodialysis, EnzymesAbstract
BACKGROUND: The present study was conducted in order to evaluate the factors affecting the adequacy of dialysis and determine the relationship of dialysis adequacy with laboratory parameters.
METHODS: This descriptive study was performed on 60 hemodialysis patients of Razi Medical Center of Qaemshahr, Iran, with the history of more than 3 months of dialysis. The participants were selected using census method. Data collection was conducted through a researcher-made questionnaire. Blood samples were collected to evaluate laboratory parameters. The adequacy of dialysis was calculated through the Kt/V parameter. The obtained data were analyzed using descriptive statistical tests.
RESULTS: According to the Kt/V criteria, the mean dialysis adequacy index was 1.6 ± 0.22 and 41.7% of the patients had the optimum dialysis adequacy (Kt/V of greater than 1.2), and 43.3% of patients had a dialysis adequacy which was close to the desirable level. There was a significant reverse relationship between dialysis adequacy and alkaline phosphatase (ALP), blood sugar, and body mass index (BMI). Nevertheless, there was no significant relationship between dialysis adequacy and parathyroid hormone (PTH), cholesterol, triglycerides, alanine aminotransferase (ALT), aspartate aminotransferase (AST), calcium, phosphorus, and the number of dialysis sessions per week, duration of each dialysis session, and the history of dialysis (P > 0.05).
CONCLUSION: In order to increase the adequacy of dialysis, the blood sugar level of patients should be controlled and patients should be advised to modify their weight using a suitable diet.
References
Shahdadi H, Badakhsh M, Masinaei N, Heydari M, Rahnama M. The effect of increasing blood flow rate on complications and dialysis adequacy in hemodialysis patients with low KT/V. Iran J Nurs Res 2010; 5(17): 62-7. [In Persian].
Nadi E, Bashirian S, Khosravi M. Assessing of dialysis adequacy in patients under hemodialysis in dialysis department of ekbatan hospital in Hamadan. Sci J Hamdan Univ Med Sci 2003; 10(3): 27-33. [In Persian].
Hojjat M. Hemodialysis adequacy in patients with chronic renal failure. Iran J Crit Care Nurs 2009; 2(2): 61-6. [In Persian].
Mogharab M, Madarshahian F, Rezai N, Mohammadi A. Dialysis adequacy in chronic hemodialysis patients in educational center Vali-Asr in Birjand. J Birjand Univ Med Sci 2010; 17(3): 206-14. [In Persian].
Behzadnia S, Davoudi A, Rezai MS, Ahangarkani F. Nosocomial infections in pediatric population and antibiotic resistance of the causative organisms in north of Iran. Iran Red Crescent Med J 2014; 16(2): e14562.
Beiranvand E, Abediankenari S, Rezaei MS, Khani S, Sardari S, Beiranvand B. Increased expression of forkhead box protein 3 gene of regulatory T cells in patients with active tuberculosis. Inflamm Allergy Drug Targets 2014; 13(5): 330-4.
Tayyebi A, Shasti S, Ebadi A, Eynollahi B, Tadrisi SD. The relationship between blood pressure and dialysis adequacy in dialysis patients. Iran J Crit Care Nurs 2012; 5(1): 49-52. [In Persian].
Joukar F, Khalesi AA, Besharati S. Distribution of HCV genotypes in hemodialytic patients of Guilan (The North Province of Iran). J Med Counc I R Iran 2010; 28(3): 277-84.
Khoushbaten M, Zali MR, Taremi M, Gachkar L, Argani H, Mahmoud Arabi SM, et al. Anti-hepatitis e virus antibody in hemodialysis patients: A seroepidemiological survey in Iran. Pejouhandeh 2005; 9(6): 323-6. [In Persian].
Mousavi Movahed SM, Tabaraie Y, Zakeriannejad M. Relationship between calcium phosphorous and parathoromone with calcification of heart valves in dialyzed patients in Qom 2006-2007. Qom Univ Med Sci J 2008; 2(1): 21-6. [In Persian].
Raeisifar A, Torabpour M, Mohsenizad P, Tayebi A, Masoumi M. Dialysis adequacy in patients of Abadan hemodialysis center. Iran J Crit Care Nurs 2009; 2(3): 87-90. [In Persian].
Monfared A, Khosravi M, Orang-poor R, Moosavian Roshan-zamir S, Aghajani Nargesi D. Reasons of chronic renal failure in hemodialysis patients in Guilan province. Jour Guilan Uni Med Sci 2003; 12(46): 76-83.
Baradaran A, Nasri H, Ganji F. The role of secondary hyperparathyroidism in anemia of end stage renal disease. Iran J Endocrinol Metab 2004; 5(4): 277-82.
Zerati A, Naghibi M, Jabbari Noghabi H. Factors affecting the adequacy of dialysis in patients undergoing hemodialysis. Med J Mashad Univ Med Sci 2008; 51(1): 45-52. [In Persian].
Roozitalab M, Moohamadi B, Najafi S, Mehrabi S. Determining the adequacy of hemodialysis in hemodialysis units of Kohgilouyeh and Boyerahmad Hospitals in 2009. Armaghane-Danesh 2010; 15(3): 273-82. [In Persian].
