The role of fatigue and depression in illness perception of patients with Multiple Sclerosis

Mohammad Hossein Abdollahi, Mahnaz Shahgholian, Shahab Baheshmat

DOI: 10.22122/cdj.v4i2.222

Abstract


BACKGROUND: Fatigue and depression affect the illness perception of patients with multiple sclerosis (MS). The purpose of the present study was to investigate the role of fatigue and depression in illness perception of patients with MS.

METHODS: The present study was a descriptive correlational research. The target population was all patients with MS who referred to the Iranian MS Society. The sample consisted of 138 patients who were selected using convenience sampling. Data were gathered using the Fatigue Severity Scale (FSS), Beck Depression Inventory (BDI), and Brief Illness Perception Questionnaire (Brief IPQ) and were analyzed via stepwise regression analysis and Pearson's correlation coefficient.

RESULTS: Based on study findings, fatigue and depression had a statistically significant relationship with all subscales of illness perception. The results of stepwise regression analysis indicated that fatigue and depression predict disease outcome, personal control, therapeutic‎ control, identity, concern, illness recognition, and emotion regulation among patients with MS.

CONCLUSION: The findings of this research showed that illness perception, as an effective indicator in patient's quality of life (QOL), appears to be predicted by fatigue and depression.


Keywords


Fatigue; Depression; Perception; Multiple Sclerosis

Full Text:

PDF

References


Fricska-Nagy Z, Fuvesi J, Rozsa C, Komoly S, Jakab G, Csepany T, et al. The effects of fatigue, depression and the level of disability on the health-related quality of life of glatiramer acetate-treated relapsing-remitting patients with multiple sclerosis in Hungary. Mult Scler Relat Disord 2016; 7: 26-32.

Fischer A, Schroder J, Vettorazzi E, Wolf OT, Pottgen J, Lau S, et al. An online programme to reduce depression in patients with multiple sclerosis: A randomised controlled trial. Lancet Psychiatry 2015; 2(3): 217-23.

Ifantopoulou N, Artemiadis K, Triantafyllou N, Chrousos G, Papanastasiou I, Darviri C. Self-esteem is associated with perceived stress in multiple sclerosis patients. Neurol Res 2015; 37(7): 588-92.

Maurer M, Comi G, Freedman MS, Kappos L, Olsson TP, Wolinsky JS, et al. Multiple sclerosis relapses are associated with increased fatigue and reduced health-related quality of life-A post hoc analysis of the TEMSO and TOWER studies. Mult Scler Relat Disord 2016; 7: 33-40.

Moscarello MA, Lei H, Mastronardi FG, Winer S, Tsui H, Li Z, et al. Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis. Dis Model Mech 2013; 6(2): 467-78.

Opara JA, Brola W, Leonardi M, Blaszczyk B. Quality of life in Parkinson's disease. J Med Life 2012; 5(4): 375-81.

Mokhtary S. The effect of group cognitive-behavioral therapy on depression of multiple sclerosis patients [MSc Thesis]. Isfahan, Iran: University of Isfahan; 2005. [In Persian].

Zarbo IR, Minacapelli E, Falautano M, Demontis S, Carpentras G, Pugliatti M. Personality traits predict perceived health-related quality of life in persons with multiple sclerosis. Mult Scler 2016; 22(4): 551-8.

Hadgkiss EJ, Jelinek GA, Weiland TJ, Pereira NG, Marck CH, van der Meer DM. The association of diet with quality of life, disability, and relapse rate in an international sample of people with multiple sclerosis. Nutr Neurosci 2015; 18(3): 125-36.

Labiano-Fontcuberta A, Mitchell AJ, Moreno-Garcia S, Benito-Leon J. Cognitive impairment in patients with multiple sclerosis predicts worse caregiver's health-related quality of life. Mult Scler 2014; 20(13): 1769-79.

Bassi M, Falautano M, Cilia S, Goretti B, Grobberio M, Pattini M, et al. Illness perception and well-being among persons with multiple sclerosis and their caregivers. J Clin Psychol Med Settings 2016; 23(1): 33-52.

Stafford L, Berk M, Jackson HJ. Are illness perceptions about coronary artery disease predictive of depression and quality of life outcomes? J Psychosom Res 2009; 66(3): 211-20.

Wilski M, Tasiemski T. Illness perception, treatment beliefs, self-esteem, and self-efficacy as correlates of self-management in multiple sclerosis. Acta Neurol Scand 2016; 133(5): 338-45.

Petrie KJ, Weinman J. Why illness perceptions matter. Clin Med (Lond) 2006; 6(6): 536-9.

Foxwell R, Morley C, Frizelle D. Illness perceptions, mood and quality of life: A systematic review of coronary heart disease patients. J Psychosom Res 2013; 75(3): 211-22.

Price A, Goodwin L, Rayner L, Shaw E, Hansford P, Sykes N, et al. Illness perceptions, adjustment to illness, and depression in a palliative care population. J Pain Symptom Manage 2012; 43(5): 819-32.

Philip EJ, Lindner H, Lederman L. Relationship of illness perceptions with depression among individuals diagnosed with lupus. Depress Anxiety 2009; 26(6): 575-82.

Sawicki GS, Sellers DE, Robinson WM. Associations between illness perceptions and health-related quality of life in adults with cystic fibrosis. J Psychosom Res 2011; 70(2): 161-7.

Broadbent E, Ellis CJ, Thomas J, Gamble G, Petrie KJ. Further development of an illness perception intervention for myocardial infarction patients: A randomized controlled trial. J Psychosom Res 2009; 67(1): 17-23.

Zyrianova Y, Kelly BD, Sheehan J, McCarthy C, Dinan TG. The psychological impact of arthritis: The effects of illness perception and coping. Ir J Med Sci 2011; 180(1): 203-10.

Hoang H, Laursen B, Stenager EN, Stenager E. Psychiatric co-morbidity in multiple sclerosis: The risk of depression and anxiety before and after MS diagnosis. Mult Scler 2016; 22(3): 347-53.

Mrabet S, Ben AN, Kchaou M, Belal S. Depression in multiple sclerosis. Rev Neurol (Paris) 2014; 170(11): 700-2.

Costa EC, Vale S, Sobral M, Graca PM. Illness perceptions are the main predictors of depression and anxiety symptoms in patients with chronic pain. Psychol Health Med 2015; 1-13.

Shallcross AJ, Becker DA, Singh A, Friedman D, Montesdeoca J, French J, et al. Illness perceptions mediate the relationship between depression and quality of life in patients with epilepsy. Epilepsia 2015; 56(11): e186-e190.

Steca P, Greco A, Monzani D, Politi A, Gestra R, Ferrari G, et al. How does illness severity influence depression, health satisfaction and life satisfaction in patients with cardiovascular disease? The mediating role of illness perception and self-efficacy beliefs. Psychol Health 2013; 28(7): 765-83.

Alsen P, Eriksson M. Illness perceptions of fatigue

and the association with sense of coherence and stress in patients one year after myocardial infarction. J Clin Nurs 2016; 25(3-4): 526-33.

Grayson PC, Amudala NA, Mcalear CA, Leduc RL, Shereff D, Richesson R, et al. Illness perceptions and fatigue in systemic vasculitis. Arthritis Care Res (Hoboken) 2013; 65(11): 1835-43.

Russo M, Crupi D, Naro A, Avanzino L, Buccafusca M, Dattola V, et al. Fatigue in patients with multiple sclerosis: From movement preparation to motor execution. J Neurol Sci 2015; 351(1-2): 52-7.

Bakalidou D, Giannopoulos S, Voumvourakis K. Annual fatigue and depression fluctuation in multiple sclerosis patients. Ann Phys Rehabil Med 2014; 57: e304-e305.

Labuz-Roszak B, Kubicka-Baczyk K, Pierzchala K, Machowska-Majchrzak A, Skrzypek M. Fatigue and its association with sleep disorders, depressive symptoms and anxiety in patients with multiple sclerosis. Neurol Neurochir Pol 2012; 46(4): 309-17.

Akaishi T, Nakashima I, Misu T, Fujihara K, Aoki M. Depressive state and chronic fatigue in multiple sclerosis and neuromyelitis optica. J Neuroimmunol 2015; 283: 70-3.

Rizou I, De G, V, Papavasiliou A, Maes S. The contribution of illness perceptions to fatigue and sleep problems in youngsters with epilepsy. Eur J Paediatr Neurol 2016; 20(1): 93-9.

Shahvarughi Farahani A, Azimian M, Fallahpour M, Karimlou M. Evaluation of reliability and validity of the Persian version of fatigue severity scale (FSS) among persons with multiple sclerosis. Rehabilitation 2013; 13(4): 84-91. [In Persian].

Steer RA, Beck AT, Garrison B. Applications of the beck depression inventory. In: Sartorius N, Ban TA, Editors. Assessment of depression. Berlin, Germany: Springer-Verlag; 1986. p. 123-42.

Bagherian Sararoudi R, Bahrami Ehsan H, Sanei H. Relationship between history of myocardial infraction and cognitive representation of myocardial infraction. Research in Psychological Health 2008; 2(2): 29-39. [In Persian].


Refbacks

  • There are currently no refbacks.


Creative Commons Attribution-NonCommercial 4.0

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.