The prevalence of allergic reaction in acute complications of injection of packed red blood cell in patients hospitalized in Sina Hospital, Kamyaran City, Iran, during the years 2014-2018

Pooya Valizadeh-Ardalan, Mohammad Jafar Baghernasab, Hero Yazdanpanah, Karo Servatyari

DOI: 10.22122/cdj.v0i0.515


BACKGROUND: Acute complications are among the most common complications in blood transfusion reactions and one of the leading causes of death. The reduction in acute complications as well as blood safety and health of patients should be considered. The aim of this short report study is to determine the prevalence of allergic reactions in acute complications of packed red blood cell (RBC) injections in patients hospitalized in Sina Hospital, Kamyaran City, Iran, from 2014 to 2018.

METHODS: This was a retrospective cross-sectional study with the statistical population including all patients who required blood transfusion in Sina hospital in Kamyaran City since 2014 to 2018. The standard checklist called "A form of reporting unwanted complications after blood transfusions and its related products" was used in this study. Data were entered into the SPSS statistical software. Descriptive statistics were analyzed as mean and standard deviation (SD) and analytical results were analyzed using Fisher's exact test.

RESULTS: In this study, the prevalence of transfusion complications during this period was 0.016. 5 (29%) and 12 (71%) of the patients were men and women, respectively. The most common sign of blood transfusion included restlessness and tachycardia. The most common acute complication of blood transfusions was allergic reaction (47%). Based on the Fisher's exact test, a statistically significant relationship was found between the blood group, sex, and history of injection with the diagnosis of transfusion (P < 0.001).

CONCLUSION: Registering the complications of blood transfusion is always a concern and important for the blood transfusion organization. In this study, it was found that the most common acute complication of blood transfusions was allergic reactions (8 out of 17).


Allergy Reaction; Blood Transfusions; Transfusion Reaction; Blood Safety; Iran

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