The prevalence of allergic reaction in acute complications of injection of packed red blood cell in patients hospitalized in Sina Hospital, Kamyaran City, Iran, during the years 2014-2018
DOI:
https://doi.org/10.22122/cdj.v8i2.515Keywords:
Allergy Reaction, Blood Transfusions, Transfusion Reaction, Blood Safety, IranAbstract
BACKGROUND: Acute complications are among the most common complications in blood transfusion reactions and one of the leading causes of death. The reduction in acute complications as well as blood safety and health of patients should be considered. The aim of this short report study is to determine the prevalence of allergic reactions in acute complications of packed red blood cell (RBC) injections in patients hospitalized in Sina Hospital, Kamyaran City, Iran, from 2014 to 2018.
METHODS: This was a retrospective cross-sectional study with the statistical population including all patients who required blood transfusion in Sina hospital in Kamyaran City since 2014 to 2018. The standard checklist called "A form of reporting unwanted complications after blood transfusions and its related products" was used in this study. Data were entered into the SPSS statistical software. Descriptive statistics were analyzed as mean and standard deviation (SD) and analytical results were analyzed using Fisher's exact test.
RESULTS: In this study, the prevalence of transfusion complications during this period was 0.016. 5 (29%) and 12 (71%) of the patients were men and women, respectively. The most common sign of blood transfusion included restlessness and tachycardia. The most common acute complication of blood transfusions was allergic reaction (47%). Based on the Fisher's exact test, a statistically significant relationship was found between the blood group, sex, and history of injection with the diagnosis of transfusion (P < 0.001).
CONCLUSION: Registering the complications of blood transfusion is always a concern and important for the blood transfusion organization. In this study, it was found that the most common acute complication of blood transfusions was allergic reactions (8 out of 17).
References
Sullivan MT, Cotten R, Read EJ, Wallace EL. Blood collection and transfusion in the United States in 2001. Transfusion 2007; 47(3): 385-94.
Dehghan Nayeri N, Arab Ameri Z, Seylani K. Patient's Safety during Blood Transfusions in Hospitals Affiliated with Tehran University of Medical Sciences. Iran J Nurs 2016; 28(98): 39-49. [In Persian].
Bodaghkhan F, Ramzi M, Vazirian S, Ahmadi M, Hajebi Rajabi M, Kohan N, et al. The prevalence of acute blood transfusion reactions in Nemazee Hospital. Sci J Iran Blood Transfus Organ 2014; 11(3): 247-51. [In Persian].
Dzik S, Aubuchon J, Jeffries L, Kleinman S, Manno C, Murphy MF, et al. Leukocyte reduction of blood components: public policy and new technology. Transfus Med Rev 2000; 14(1): 34-52.
Shams-Asanjan K, Zolfaghari S, Balali MR, Mardani A, Niakan G. Clinical training for blood transfusion personnel using the experiences of the Hemvogelians system in Iran and the United Kingdom, Tehran, Iran [Online]. [cited 2014]; Available from: URL: www.ibto.ir/uploads/Hemovigilance_learning_Iran-England.pdf
Teimuri H, Imani F, Maghsudlu M, Kia Daliri K, Fallah Tafti M. Prevalence of acute blood transfusion reactions in 11 hospitals of Tehran and Mazandaran province. Sci J Iran Blood Transfus Organ 2007; 4(1): 19-24. [In Persian].
Henneman EA, Roche JP, Fisher DL, Cunningham H, Reilly CA, Nathanson BH, et al. Error identification and recovery by student nurses using human patient simulation: Opportunity to improve patient safety. Appl Nurs Res 2010; 23(1): 11-21.
Aminiahidashti H, Bozorgi F, Montazer H, Zeinali F, Seyed Jaber S J. Acute Outcomes of Blood Transfusions in Patients Admitted to Emergency Department. J Mazandaran Univ Med Sci 2016; 25(134): 324-8. [In Persian].
Silliman CC, Boshkov LK, Mehdizadehkashi Z, Elzi DJ, Dickey WO, Podlosky L, et al. Transfusion-related acute lung injury: Epidemiology and a prospective analysis of etiologic factors. Blood 2003; 101(2): 454-62.
Tajali S, Tatarpour P, Fallahi M. RBC Transfusion in premature neonates in Mofid Children Hospital 2017. Sci J Iran Blood Transfus Organ 2018; 15(1): 47-54. [In Persian].
Kato H, Nakayama T, Uruma M, Okuyama Y, Handa M, Tomiyama Y, et al. A retrospective observational study to assess adverse transfusion reactions of patients with and without prior transfusion history. Vox Sang 2015; 108(3): 243-50.
Salimi S, Feizi A, Vanabadi N. Incidence rate of acute reactions in transfusion of blood and its products prepared by Urumia Blood Refinery Center. Advances in Nursing and Midwifery 2010; 16(66):
-13. [In Persian].
Asvadi Kermani I, Eyvazi Ziaei J, Nikanfar AR, Maljaie H, Golchin M, Berahmani G, et al. Blood transfusion acute reactions in patients of Shahid Ghazi Hospital. Sci J Iran Blood Transfus Organ 2006; 2(6): 215-20. [In Persian].
Rossi EC, Simon TL, Dzik WH, Stowell CP. Rossi's Principles of Transfusion Medicine. Philadelphia, PA: Lippincott Williams & Wilkins; 2002.
