Impacts of osteoporosis on quality of life in elderly women
DOI:
https://doi.org/10.22122/cdj.v1i1.18Keywords:
Quality of Life, Osteoporosis, Menopause, Female, Qualeffo-41 QuestionnaireAbstract
BACKGROUND: Osteoporosis, the most common pathological cause of skeletal weakening and the most common metabolic bone disease, is caused by loss of bone mass density (BMD). Fractures due to osteoporosis will worsen life, increase pain, and decrease quality of life. The present study aimed to determine the impact of osteoporosis on quality of life among elderly women.
METHODS: In a cross-sectional study, 275 postmenopausal women (age: 50-70 years) who were referred to the Namazi Hospital (Shiraz, Iran) were included. BMD was measured according to the World Health Organization (WHO) standards. Women with BMD < -2.5 standard deviation (SD) of the average value in young adults were defined as osteoporosis cases. Women with BMD > 1 SD of the average value were defined as normal cases. Quality of life was measured by Qualeffo-41 Questionnaire and reported on a scale of 100. Data was analyzed in SPSS and P values less than 0.05 were considered significant.
RESULTS: The mean quality of life score was 25.5 ± 11.7. According to the definition by the WHO, 70.2% of the participants were affected with osteoporosis. Only 22.3% of osteoporotic women and 30.5% of normal subjects had good quality of life. A significant statistical difference was observed between osteoporotic and normal postmenopausal women in social activities. Overweight and low education were predictors of poor quality of life in multivariate analysis.
CONCLUSION: The imposed financial burden and complications of osteoporosis can affect the patients’ quality of life. Health education regarding nutritional behaviors and social activities at adolescence are helpful interventions for decreasing the prevalence of the disease. Since osteoporosis has a gradual, outward, and asymptomatic trend, more attention needs to be paid to preventive and screening programs.
References
Cortet B, Blotman F, Debiais F, Huas D, Mercier F, Rousseaux C, et al. Management of osteoporosis and associated quality of life in post menopausal women. BMC Musculoskelet Disord 2011; 12: 7.
Johnell O, Kanis J. Epidemiology of osteoporotic fractures. Osteoporos Int 2005; 16(Suppl 2): S3-S7.
Bagheri P, Haghdoost AA, Dortaj Raberi E, Halimi L, Vafaei Z, Farhang Nya M, et al. Ultra Analysis of Prevalence of Osteoporosis in Iranian Women "A Systematic Review and Meta-analysis". Iran J of Endocrinol Metab 2011; 13(3): 315-25.
Borgstrom F, Zethraeus N, Johnell O, Lidgren L, Ponzer S, Svensson O, et al. Costs and quality of life associated with osteoporosis-related fractures in Sweden. Osteoporos Int 2006; 17(5): 637-50.
Dempster DW. Osteoporosis and the burden of osteoporosis-related fractures. Am J Manag Care 2011; 17(Suppl 6): S164-S169.
Palacios S, Borrego RS, Forteza A. The importance of preventive health care in post-menopausal women. Maturitas 2005; 52(Suppl 1): S53-S60.
Rajaeefard A, Mohammad-Beigi A, Mohammad-Salehi N. Estimation of natural age of menopause in Iranian women: a meta-analysis study. Koomesh 2011; 13(1): 1-7.
Gullberg B, Johnell O, Kanis JA. World-wide projections for hip fracture. Osteoporos Int 1997; 7(5): 407-13.
Johnell O. The socioeconomic burden of fractures: today and in the 21st century. Am J Med 1997; 103(2A): 20S-5S.
Hagino H, Furukawa K, Fujiwara S, Okano T, Katagiri H, Yamamoto K, et al. Recent trends in the incidence and lifetime risk of hip fracture in Tottori, Japan. Osteoporos Int 2009; 20(4): 543-8.
Cook DJ, Guyatt GH, Adachi JD, Clifton J, Griffith LE, Epstein RS, et al. Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993; 36(6): 750-6.
Borer KT. Physical activity in the prevention and amelioration of osteoporosis in women : interaction of mechanical, hormonal and dietary factors. Sports Med 2005; 35(9): 779-830.
Martin AR, Sornay-Rendu E, Chandler JM, Duboeuf F, Girman CJ, Delmas PD. The impact of osteoporosis on quality-of-life: the OFELY cohort. Bone 2002; 31(1): 32-6.
Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser 1994; 843: 1-129.
Cook DJ, Guyatt GH, Adachi JD, Epstein RS, Juniper EF, Austin PA, et al. Development and validation of the mini-osteoporosis quality of life questionnaire (OQLQ) in osteoporotic women with back pain due to vertebral fractures. Osteoporosis Quality of Life Study Group. Osteoporos Int 1999; 10(3): 207-13.
Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, et al. Quality of life in patients with vertebral fractures: validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Working Party for Quality of Life of the European Foundation for Osteoporosis. Osteoporos Int 1999; 10(2): 150-60.
Murrell P, Todd CJ, Martin A, Walton J, Lips P, Reeve J. Postal administration compared with nurse-supported administration of the QUALEFFO-41 in a population sample: comparison of results and assessment of psychometric properties. Osteoporos Int 2001; 12(8): 672-9.
Badia X, Diez-Perez A, Alvarez-Sanz C, Diaz-Lopez B, Diaz-Curiel M, Guillen F, et al. Measuring quality of life in women with vertebral fractures due to osteoporosis: a comparison of the OQLQ and QUALEFFO. Qual Life Res 2001; 10(4): 307-17.
Bianchi ML, Orsini MR, Saraifoger S, Ortolani S, Radaelli G, Betti S. Quality of life in post-menopausal osteoporosis. Health Qual Life Outcomes 2005; 3: 78.
Kocyigit H, Gulseren S, Erol A, Hizli N, Memis A. The reliability and validity of the Turkish version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Clin Rheumatol 2003; 22(1): 18-23.
Salaffi F, Stancati A, Carotti M, Lorenzetti R, Grassi W. The impact of vertebral fractures on quality of life in postmenopausal women with osteoporosis. Validity of the Italian version of mini-Osteoporosis Quality of Life Questionnaire. Reumatismo 2005; 57(2): 83-96. [In Italian].
Huas D, Debiais F, Blotman F, Cortet B, Mercier F, Rousseaux C, et al. Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment. BMC Womens Health 2010; 10: 26.
Tosteson AN, Gabriel SE, Grove MR, Moncur MM, Kneeland TS, Melton LJ, III. Impact of hip and vertebral fractures on quality-adjusted life years. Osteoporos Int 2001; 12(12): 1042-9.
Silverman SL, Minshall ME, Shen W, Harper KD, Xie S. The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 2001; 44(11): 2611-9.
Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, et al. Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000; 15(7): 1384-92.
Silverman SL. Quality-of-life issues in osteoporosis. Curr Rheumatol Rep 2005; 7(1): 39-45.
Mitchell C. Assessment and management of chronic pain in elderly people. Br J Nurs 2001; 10(5): 296-304.